PD-L1-IN-8
PD-L1-IN-8 is a PD-L1 inhibitor (IC50 = 0.89 nM). PD-L1-IN-8 shows low CYP inhibition and minimal hERG activity. PD-L1-IN-8 can be used for the study of colon cancer.
For research use only. We do not sell to patients.
- CAS No.: 3104751-99-4
- Formula: C40H42ClN9O3
- Molecular Weight:732.27
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Chemical Information
-
CAS No. 3104751-99-4
-
Molecular Weight 732.27
-
Formula C40H42ClN9O3
-
SMILES
ClC(C(NC1=NC=CC2=C1N=CC(CN3CC[C@@H](O)C3)=C2)=CC=C4)=C4C5=CC=CC6=C5CCN6C(C7=NN(CCCC8NC[C@@H]9CCC(N9)=O)C8=C7)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)