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Cat. No.: HY-13781R

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Pemetrexed disodium hemipenta hydrate (Standard)

Name: Pemetrexed disodium hemipenta hydrate (Standard)
Brand: MedChemExpress
SKU: HY-13781R
Price: 30.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: LY231514 disodium hemipenta hydrate (Standard))

Pemetrexed (disodium hemipenta hydrate) (Standard) is the analytical standard of Pemetrexed (disodium hemipenta hydrate). This product is intended for research and analytical applications. Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 357166-30-4
Formula: C₂₀H₂₄N₅Na₂O_8.5
Molecular Weight:516.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pemetrexed disodium hemipenta hydrate (Standard) Chemical Structure

CAS No.: 357166-30-4

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 357166-30-4
Molecular Weight 516.41
Formula C₂₀H₂₄N₅Na₂O_8.5
SMILES

O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(CCC2=CNC(N=C(N)N3)=C2C3=O)C=C1)=O.[2.5H2O]
Synonyms

LY231514 disodium hemipenta hydrate (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Shih C, et al. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes. Cancer Res. 1997 Mar 15;57(6):1116-23. [Content Brief]

[2]. Anraku M, et al. Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignantmesothelioma. J Immunol. 2010 Jul 15;185(2):956-66. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Pemetrexed disodium hemipenta hydrate (Standard)

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Pemetrexed disodium hemipenta hydrate (Standard)