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Cat. No.: HY-186149

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Phosphate muramyl dipeptide

Phosphate muramyl dipeptide is a class of lipophilic derivatives synthesized based on the structural characteristics of mycobacterial cell walls Phosphate muramyl dipeptide can be used for the research of cancer.

For research use only. We do not sell to patients.

CAS No.: 83428-79-9
Formula: C₁₉H₃₃N₄O₁₄P
Molecular Weight:572.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Phosphate muramyl dipeptide Chemical Structure

CAS No.: 83428-79-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All NOD-like Receptor (NLR) Isoforms :

In Vitro

Phosphate muramyl dipeptide (compound 2) is a modified form of muramyl dipeptide (MDP), the minimal essential unit of bacterial peptidoglycan, which possesses immunostimulatory properties^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Phosphate muramyl dipeptide (compound 2) (100 μg/mouse; i.d.; single dose) shows no tumor growth suppression activity in mouse Meth-A fibrosarcoma models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

BALB/c (male, 5 week-old) intradermally inoculated with Meth-A fibrosarcoma cells^[1]
Dosage:

100 μg/mouse
Administration:

i.d.; single co-administration with tumor cells
Result:

Resulted in 80% tumor cell viability.
Resulted in 0 cured mice out of 9 treated mice.
Resulted in a T/C value of 91.4%.

Chemical Information

CAS No. 83428-79-9
Molecular Weight 572.46
Formula C₁₉H₃₃N₄O₁₄P
SMILES

C[C@@H](C(N[C@@H](C(N)=O)CCC(O)=O)=O)NC([C@H](O[C@H]1[C@@H]([C@H](OC([C@@H]1NC(C)=O)O)COP(O)(O)=O)O)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Imoto M, et al. Synthesis and Antitumor Activity of N-Acetylmuramyl-l-Alanyl-d-Isoglutamine 6-Phosphate and Its Lipophilic Derivatives. Bulletin of the Chemical Society of Japan 1986, 59 (10), 3207-3212.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References

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Phosphate muramyl dipeptide

All NOD-like Receptor (NLR) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Phosphate muramyl dipeptide Related Classifications

HY-186149 Related Classifications