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Art. -Nr.: HY-186149

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Phosphate muramyl dipeptide

Phosphate muramyl dipeptide is a class of lipophilic derivatives synthesized based on the structural characteristics of mycobacterial cell walls Phosphate muramyl dipeptide can be used for the research of cancer.

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CAS. Nr.: 83428-79-9
Formel: C₁₉H₃₃N₄O₁₄P
Molecular Weight:572.46

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Phosphate muramyl dipeptide Chemical Structure

CAS. Nr.: 83428-79-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle NOD-like Receptor (NLR) Isoform-spezifische Produkte anzeigen :

In Vitro

Phosphate muramyl dipeptide (compound 2) is a modified form of muramyl dipeptide (MDP), the minimal essential unit of bacterial peptidoglycan, which possesses immunostimulatory properties^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Phosphate muramyl dipeptide (compound 2) (100 μg/mouse; i.d.; single dose) shows no tumor growth suppression activity in mouse Meth-A fibrosarcoma models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

BALB/c (male, 5 week-old) intradermally inoculated with Meth-A fibrosarcoma cells^[1]
Dosage:

100 μg/mouse
Administration:

i.d.; single co-administration with tumor cells
Result:

Resulted in 80% tumor cell viability.
Resulted in 0 cured mice out of 9 treated mice.
Resulted in a T/C value of 91.4%.

Chemical Information

CAS. Nr. 83428-79-9
Molecular Weight 572.46
Formel C₁₉H₃₃N₄O₁₄P
SMILES

C[C@@H](C(N[C@@H](C(N)=O)CCC(O)=O)=O)NC([C@H](O[C@H]1[C@@H]([C@H](OC([C@@H]1NC(C)=O)O)COP(O)(O)=O)O)C)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Imoto M, et al. Synthesis and Antitumor Activity of N-Acetylmuramyl-l-Alanyl-d-Isoglutamine 6-Phosphate and Its Lipophilic Derivatives. Bulletin of the Chemical Society of Japan 1986, 59 (10), 3207-3212.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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