2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. Piperidine-GNE-049-N-Boc

Piperidine-GNE-049-N-Boc 

Cat. No.: HY-134592 Purity: 98.82%
COA Handling Instructions

Piperidine-GNE-049-N-Boc is a ligand for target protein for PROTAC of dCBP-1 (HY-134582). dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP.

For research use only. We do not sell to patients.

Piperidine-GNE-049-N-Boc Chemical Structure

Piperidine-GNE-049-N-Boc Chemical Structure

CAS No. : 1936431-36-5

Size Price Stock Quantity
5 mg USD 950 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
25 mg USD 3450 In-stock
Estimated Time of Arrival: December 31
50 mg USD 5500 In-stock
Estimated Time of Arrival: December 31
100 mg USD 8600 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Piperidine-GNE-049-N-Boc is a ligand for target protein for PROTAC of dCBP-1 (HY-134582). dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].

In Vitro

Piperidine-GNE-049-N-Boc (S17) can be used for synthesizing dCBP-1[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

567.67

Appearance

Solid

Formula

C30H39F2N7O2
CAS No.
SMILES

O=C(N1CCC(N(C2CCNCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)OC(C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro: 

1M HCl : 32.5 mg/mL (57.25 mM; ultrasonic and adjust pH to 1 with HCl)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7616 mL 8.8079 mL 17.6159 mL
5 mM 0.3523 mL 1.7616 mL 3.5232 mL
10 mM 0.1762 mL 0.8808 mL 1.7616 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Keywords:

Piperidine-GNE-049-N-Boc1936431-36-5Ligands for Target Protein for PROTACTarget Protein-binding MoietyligandtargetproteinPROTACdCBP-1heterobifunctionaldegraderp300CBPInhibitorinhibitorinhibit

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