2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. Piperidine-GNE-049-N-Boc

Piperidine-GNE-049-N-Boc is a ligand for target protein for PROTAC of dCBP-1 (HY-134582). dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP.

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Piperidine-GNE-049-N-Boc

Piperidine-GNE-049-N-Boc 構造式

CAS 番号 : 1936431-36-5

容量 価格（税別） 在庫状況 数量
5 mg $218 在庫あり
10 mg $350 在庫あり
25 mg $645 在庫あり
50 mg $918 在庫あり
100 mg $1250 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Piperidine-GNE-049-N-Boc 関連抗体

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製品説明

Piperidine-GNE-049-N-Boc is a ligand for target protein for PROTAC of dCBP-1 (HY-134582). dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].

体外実験

Piperidine-GNE-049-N-Boc (S17) can be used for synthesizing dCBP-1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Piperidine-GNE-049-N-Boc 関連抗体
分子量

567.67

分子式

C30H39F2N7O2
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CCC(N(C2CCNCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)OC(C)(C)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外: 

1M HCl : 32.5 mg/mL (57.25 mM; ultrasonic and adjust pH to 1 with HCl)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7616 mL 8.8079 mL 17.6159 mL
5 mM 0.3523 mL 1.7616 mL 3.5232 mL
10 mM 0.1762 mL 0.8808 mL 1.7616 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

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体積 （開始）

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濃度 （終了）

C2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
1M HCl 1 mM 1.7616 mL 8.8079 mL 17.6159 mL 44.0397 mL
5 mM 0.3523 mL 1.7616 mL 3.5232 mL 8.8079 mL
10 mM 0.1762 mL 0.8808 mL 1.7616 mL 4.4040 mL
15 mM 0.1174 mL 0.5872 mL 1.1744 mL 2.9360 mL
20 mM 0.0881 mL 0.4404 mL 0.8808 mL 2.2020 mL
25 mM 0.0705 mL 0.3523 mL 0.7046 mL 1.7616 mL
30 mM 0.0587 mL 0.2936 mL 0.5872 mL 1.4680 mL
40 mM 0.0440 mL 0.2202 mL 0.4404 mL 1.1010 mL
50 mM 0.0352 mL 0.1762 mL 0.3523 mL 0.8808 mL
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Piperidine-GNE-049-N-Boc Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Piperidine-GNE-049-N-Boc1936431-36-5Ligands for Target Protein for PROTACTarget Protein-binding MoietyligandtargetproteinPROTACdCBP-1heterobifunctionaldegraderp300CBPInhibitorinhibitorinhibit

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製品名:
Piperidine-GNE-049-N-Boc
製品番号:
HY-134592
数量:
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