(+)-ε-Viniferin
(+)-ε-Viniferin is a stilbenes compound with PGE2 inhibition effect, and is an orally active anti-inflammatory agent. ε-viniferin is also able to reduce fat accumulation, thus can be used for research of inflammation or obesity.
For research use only. We do not sell to patients.
- CAS No.: 129170-22-5
- Formula: C28H22O6
- Molecular Weight:454.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-375 | EC50 |
>100 μM
Compound: (+/-)-Epsilon-viniferin
|
Antiproliferative activity against human A375 cells after 72 hrs by MTT assay
Antiproliferative activity against human A375 cells after 72 hrs by MTT assay
|
[PMID: 25826398] |
| A549 | EC50 |
>100 μM
Compound: (+/-)-Epsilon-viniferin
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 25826398] |
| HCT-116 | EC50 |
>100 μM
Compound: (+/-)-Epsilon-viniferin
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 25826398] |
| Platelet | IC50 |
>100 μM
Compound: (+)-epsilon-viniferin
|
Antiplatelet activity against citreated rabbit platelet assessed as arachidonic acid-induced platelet aggregation
Antiplatelet activity against citreated rabbit platelet assessed as arachidonic acid-induced platelet aggregation
|
[PMID: 15730246] |
| Platelet | IC50 |
>100 μM
Compound: (+)-epsilon-viniferin
|
Antiplatelet activity against citreated rabbit platelet assessed as inhibition of 9,11-dideoxy-11 alpha, 9 alpha epoxy-methanoprostaglandin F2alpha-induced platelet aggregation
Antiplatelet activity against citreated rabbit platelet assessed as inhibition of 9,11-dideoxy-11 alpha, 9 alpha epoxy-methanoprostaglandin F2alpha-induced platelet aggregation
|
[PMID: 15730246] |
| SK-MEL-2 | EC50 |
>100 μM
Compound: (+/-)-Epsilon-viniferin
|
Antiproliferative activity against human SK-MEL-2 cells after 72 hrs by MTT assay
Antiproliferative activity against human SK-MEL-2 cells after 72 hrs by MTT assay
|
[PMID: 25826398] |
Chemical Information
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CAS No. 129170-22-5
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Molecular Weight 454.47
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Formula C28H22O6
-
SMILES
OC(C=C1)=CC=C1/C=C/C2=C3[C@H](C4=CC(O)=CC(O)=C4)[C@@H](C5=CC=C(C=C5)O)OC3=CC(O)=C2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang KT, et al. Anti-inflammatory effects of resveratrol and oligostilbenes from Vitis thunbergii var. taiwaniana against lipopolysaccharide-induced arthritis. J Agric Food Chem. 2011 Apr 27;59(8):3649-56. [Content Brief]
[2]. Gómez-Zorita S, et al. Beneficial Effects of ε-Viniferin on Obesity and Related Health Alterations. Nutrients. 2023 Feb 12;15(4):928. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)