Polyquaternium-51 

Polyquaternium-51 is a hydrophilic polymeric zwitterion with counter ions, and an artificial cell membrane-mimicking material with high biocompatibility. Polyquaternium-51 functions as a penetration inhibitor and exfoliation efficacy reducer. Polyquaternium-51 can be used as cosmetic moisturizing ingredient, and can be used as coating biological scaffolds^[1][2].

Polyquaternium-51 (4 wt% L-carnitine at a 1:1 molar ratio; 24 h) shows reduced percutaneous penetration into porcine skin SC (2.38% of applied product) and other epidermal layers (4.17% of applied product)^[2].
Polyquaternium-51 reduces percutaneous penetration of L-carnitine into epidermal layers and reduces L-carnitine exfoliation efficacy in ion-pair formulations^[2].
Polyquaternium-51 supports manufacturing blood dialysis membranes, coating biological scaffolds, forming polymer micelles, reducing non-specific adsorption on biomedical chips, coating artificial joints and blood vessels, and use as soft contact lens material or cosmetic moisturizing ingredient^[1][2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(C₁₁H₂₂NO₆P·C₈H₁₄O₂)x

125275-25-4

C[N+](C)(C)CCOP(OCCOC(C(CC)(CC(C(OCCCC)=O)(C)C)C)=O)([O-])=O.[a].[b]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Xie Tong, et al. A kind of synthetic method of artificial cell membrane material polyquaternium-51. CN 109666100 A.

  [2]. In S, Yook N, Kim JH, et al.. Enhancement of exfoliating efficacy of L-carnitine with ion-pair method monitored by nuclear magnetic resonance spectroscopy. Scientific reports. 2019 Sep 18;9(1):13507.