Potassium bromide, 99%
Based on 1 Customer Validation
Potassium bromide, 99% is a salt, widely used as an anticonvulsant and a sedative. Potassium bromide is a redox reagent that can be used to remove peripheral membrane proteins in molecular biology.
For research use only. We do not sell to patients.
- Purity : 99.16%
- CAS No.: 7758-02-3
- Formula: KBr
- Molecular Weight:119.00
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vivo
Potassium bromide, 99% (50 mg/kg/day; oral administration; once a day for 28 days) in male Wistar rats in the object recognition task significantly decreases the DI, RI and the frequency of exploration[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Wistar rats (weighing 200 ± 20 g)[1].
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Dosage:50 mg/kg, 100 mg/kg, 150 mg/kg (single-dose ); 50 mg/kg/day (long-term treatment)
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Administration:Oral administration; for acute treatment, single-dose; for long-term treatment, once a day for 28 days
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Result:In the acute treatment, a single dose of 150 mg/kg significantly decreased the discrimination and recognition indices (DI and RI) in the object recognition task.
In the long-term treatment, significantly decreased the DI, RI and the frequency of exploration in the object recognition task.
Chemical Information
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CAS No. 7758-02-3
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Appearance Solid
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Molecular Weight 119.00
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Formula KBr
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Color White to off-white
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SMILES
[K]Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (840.34 mM; Need ultrasonic)
DMSO : 33.33 mg/mL (280.08 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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ROS/oxidative-stress fluorescent staining
ROS/oxidative-stress fluorescent staining uses cell-permeant fluorogenic probes that become fluorescent after oxidation inside cells or tissues; commonly used examples include DCFH-DA/DCFDA for broad cellular oxidant detection, DHE for superoxide-related signal detection, MitoSOX for mitochondrial superoxide-related signal detection, and CellROX probes for oxidative-stress-associated fluorescence readouts. The assay detects probe oxidation rather than a single ROS species unless the probe and analysis method have been chemically validated for that species. DCFH-DA enters cells, is deacetylated by intracellular esterases to DCFH, and produces fluorescent DCF after oxidation, so the readout is used as an operational measure of total cellular oxidative stress rather than a species-specific ROS measurement. DHE and MitoSOX can report superoxide-related oxidation, but red fluorescence alone can include non-specific ethidium-like oxidation products; HPLC or optimized spectral approaches are
Purity & Documentation
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Data Sheet (276 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 8.4034 mL | 42.0168 mL | 84.0336 mL | 210.0840 mL |
| 5 mM | 1.6807 mL | 8.4034 mL | 16.8067 mL | 42.0168 mL | |
| 10 mM | 0.8403 mL | 4.2017 mL | 8.4034 mL | 21.0084 mL | |
| 15 mM | 0.5602 mL | 2.8011 mL | 5.6022 mL | 14.0056 mL | |
| 20 mM | 0.4202 mL | 2.1008 mL | 4.2017 mL | 10.5042 mL | |
| 25 mM | 0.3361 mL | 1.6807 mL | 3.3613 mL | 8.4034 mL | |
| 30 mM | 0.2801 mL | 1.4006 mL | 2.8011 mL | 7.0028 mL | |
| 40 mM | 0.2101 mL | 1.0504 mL | 2.1008 mL | 5.2521 mL | |
| 50 mM | 0.1681 mL | 0.8403 mL | 1.6807 mL | 4.2017 mL | |
| 60 mM | 0.1401 mL | 0.7003 mL | 1.4006 mL | 3.5014 mL | |
| 80 mM | 0.1050 mL | 0.5252 mL | 1.0504 mL | 2.6261 mL | |
| 100 mM | 0.0840 mL | 0.4202 mL | 0.8403 mL | 2.1008 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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