PROTAC EGFR degrader 17
PROTAC EGFR degrader 17 (Compound 35) is an EGFR PROTAC degrader with a DC50 value of 0.49 nM. PROTAC EGFR degrader 17 promotes the ubiquitination and degradation of EGFR. PROTAC EGFR degrader 17 can be used in research on various cancers, including non-small cell lung cancer.
(Pink: EGFR ligand (HY-181115); Blue: TNF Receptor ligand (HY-138793); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 3065209-64-2
- Formula: C46H51N11O5
- Molecular Weight:837.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Biological Activity
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Cereblon |
Chemical Information
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CAS No. 3065209-64-2
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Molecular Weight 837.97
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Formula C46H51N11O5
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SMILES
CN1N=CC(C2=CC(C(/N=C3N(C4)C(C=C(N5CCN(CC6CN(C7=CC(CN(C8C(NC(CC8)=O)=O)C9=O)=C9C=C7)C6)CC5)C=C%10)=C%10N/3)=O)=CC(C)=N2)=C1OC[C@@H]%11C[C@H]4CC%11
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC EGFR degrader 17 Related Classifications
HY-180917 Related Classifications
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