Serpin B6b
Serpin B6b is a rodent paralog of Serpin B6 (PI6) within the intracellular clade B serpin family, arising from gene duplication in the SERPINB cluster. Like its human relative, it adopts the canonical serpin fold with a reactive-center loop positioned to trap chymotrypsin-family serine proteases, although a definitive physiological target has not been established. Transcripts have been detected in hematopoietic and neural tissues, suggesting a cytoprotective role that limits protease leakage during inflammation or apoptosis. Because functional data are sparse, recombinant Serpin B6b is primarily employed for biochemical characterization, antibody generation and for dissecting paralog redundancy in knockout models.
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Serpin B6b Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
