Quaternary isoquinoline alkaloids from Stephania cepharantha

  • Chem Pharm Bull (Tokyo). 2000 Mar;48(3):370-3. doi: 10.1248/cpb.48.370.
T Tanahashi  1 ,  U Su ,  N Nagakura ,  H Nayeshiro
Affiliations
  • 1. Kobe Pharmaceutical University, Japan.
PMID: 10726860 DOI: 10.1248/cpb.48.370
Abstract

From the quaternary alkaloidal fraction of the dried tubers of Stephania cepharantha, two new Isoquinoline Alkaloids, stecepharine and tetradehydroreticuline have been isolated along with the known compounds, magnoflorine, menisperine, steponine, cyclanoline, oblongine, cis-N-methylcapaurine and 2'-N-methylisotetrandrine. cis-N-Methylcapaurine (=9-O-methylstecepharine) was isolated as a natural product for the first time. Their structures were determined on the basis of spectroscopic evidence.

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