Catharanthus alkaloids XXXII: isolation of alkaloids from Catharanthus trichophyllus roots and structure elucidation of cathaphylline

Further examination of the cytotoxic alkaloid fractions of Catharanthus trichophyllus roots afforded nine Alkaloids. Two of these Alkaloids, lochnericine and horhammericine, are responsible for part of the cytotoxic activity. The structure elucidation of cathaphylline, a new beta-anilino acrylate derivative, is described.