Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line

  • J Nat Prod. 2004 Jan;67(1):46-8. doi: 10.1021/np030293k.
Norio Nakamura  1 ,  Akiko Hirakawa ,  Jiang-Jing Gao ,  Hiroko Kakuda ,  Motoo Shiro ,  Yasuhiro Komatsu ,  Chia-chin Sheu ,  Masao Hattori
Affiliations
  • 1. Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan.
PMID: 14738384 DOI: 10.1021/np030293k
Abstract

Five new maleic and succinic acid derivatives were isolated from the mycelium of Antrodia camphorata. Their structures were determined by various spectroscopic means. Maleimide derivatives 2 and 3 showed appreciable cytotoxic activity against LLC cells.