Oxaflozane overdose in a child

  • J Toxicol Clin Toxicol. 1992;30(1):123-6. doi: 10.3109/15563659208994452.
J P Dutertre  1 ,  P Barbier ,  A L Suc ,  A P Jonville ,  E Autret
Affiliations
  • 1. Department of Clinical Pharmacology, Centre Hospitalier Régional et Universitaire de Tours, France.
PMID: 1542141 DOI: 10.3109/15563659208994452
Abstract

A case of severe poisoning in a 2 year-old child who ingested 150 mg of oxaflozane, a non-tricyclic antidepressant, is reported. After loss of consciousness, opisthotonos and coma, recovery was obtained with conservative treatment. Atropine-like symptoms were noted. The maximal plasma concentration of oxaflozane was 63 ng/mL. The elimination half-life for N-dealkyloxaflozane was 4.8 h.

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