A new amide from Asarum forbesii Maxim

  • J Asian Nat Prod Res. 2005 Feb;7(1):1-5. doi: 10.1080/10286020310001596015.
Feng Zhang  1 ,  Chang-Hu Chu ,  Qing Xu ,  Shao-Ping Fu ,  Jie-Han Hu ,  Hong-Bin Xiao ,  Xin-Miao Liang
Affiliations
  • 1. Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
PMID: 15621594 DOI: 10.1080/10286020310001596015
Abstract

A highly unsaturated new amide, (2E,4Z,8Z,10Z)-N-isobutyl-2,4,8,10-dodecatetraenamide (1), was isolated in very small quantities from the whole plant of Asarum forbesii Maxim. together with four known compounds, (2E,4E,8Z,10E)-N-isobutyl-2,4,8,10-dodecatetraenamide (2), (-)-sesamin (3), (-)-asarinin (4) and (E)-asarone (5). The Z/E isomers, 1 and 2, were separated successfully by developed silver-ion medium-pressure liquid chromatography (SIMPLC). Compound 2 and the two diastereoisomers, 3 and 4, were isolated from this plant for the first time. The characterization of these compounds was achieved by various spectroscopic methods.

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