3-Thio-1,2,4-triazoles, novel somatostatin sst2/sst5 agonists

  • Bioorg Med Chem Lett. 2005 Aug 1;15(15):3555-9. doi: 10.1016/j.bmcl.2005.05.061.
Marie-Odile Contour-Galcéra  1 ,  Alban Sidhu ,  Pascale Plas ,  Pierre Roubert
Affiliations
  • 1. Ipsen Research Laboratories, Institut Henri Beaufour, 5 Avenue du Canada, F-91966 Les Ulis Cédex, France. [email protected]
PMID: 15982879 DOI: 10.1016/j.bmcl.2005.05.061
Abstract

Novel 3-thio-1,2,4-triazoles have been obtained via a solution-phase parallel synthesis strategy, affording potent non-peptidic human Somatostatin Receptor subtypes 2 and 5 agonists.