Cytotoxic phenylpropanoid glycosides from the stems of Smilax china

  • J Nat Prod. 2005 Oct;68(10):1475-8. doi: 10.1021/np050109q.
Yao-Haur Kuo  1 ,  Ya-Wen Hsu ,  Chia-Ching Liaw ,  Jiun Kuan Lee ,  Hui-Chi Huang ,  Li-Ming Yang Kuo
Affiliations
  • 1. National Research Institute of Chinese Medicine, Taipei, 112 Taiwan, Republic of China. [email protected]
PMID: 16252910 DOI: 10.1021/np050109q
Abstract

Bioassay-guided fractionation of an ethanol extract of Smilax china led to the isolation of nine Phenylpropanoids including six new compounds, smilasides A-F (1-6), and three known Phenylpropanoids, smiglaside E, heloniosides B, and 2',6'-diacetyl-3,6-diferuloylsucrose. Structural elucidation of isolates 1-6 was based on spectroscopic data analysis. These new Phenylpropanoids were evaluated against several human tumor cell lines.