An alkaloid, two conjugate sesquiterpenes and a phenylpropanoid from Pachypodanthium confine Engl. and Diels

  • Phytochemistry. 2007 Jul;68(13):1813-8. doi: 10.1016/j.phytochem.2007.04.001.
Hilarion Mathouet  1 ,  Abdelhakim Elomri ,  Pedro Lameiras ,  Adam Daïch ,  Philippe Vérité
Affiliations
  • 1. Laboratoire de Pharmacognosie, UMR 6014-CNRS, Université de Rouen, Faculté de Pharmacie, 22 Boulevard Gambetta, F-76183 Rouen Cedex 1, France.
PMID: 17544038 DOI: 10.1016/j.phytochem.2007.04.001
Abstract

Two sesquiterpene-trimethoxystyrene conjugates (E)-1-[3'-(4'',8''-dimethylnona-3'',7''-dienyl)cyclohex-3'-enyl]-2,4,5-trimethoxybenzene (1) and (Z)-1-[3'-(4'',8''-dimethylnona-3'',7''-dienyl)cyclohex-3'-enyl]-2,4,5-trimethoxybenzene (2), a phenylpropanoid 1,2,4-trimethoxy-5-(1-methoxy-ethyl)-benzene (3), and an aporphine alkaloid N-acetylpachypodanthine (4), were isolated in addition to several known compounds from cyclohexane, dichloromethane and alkaloid extracts from bark of Pachypodanthium confine. The structures of these compounds were established based on the interpretation of their high resolution NMR (HSQC, HMBC, COSY and NOESY) spectral data.

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