Trijugin-type limonoids from the leaves of Cipadessa cinerascens

  • J Nat Prod. 2007 Aug;70(8):1352-5. doi: 10.1021/np0700624.
Ying-Tong Di  1 ,  Hong-Ping He ,  Hai-Yang Liu ,  Ping Yi ,  Zhen Zhang ,  Yan-Li Ren ,  Jun-Song Wang ,  Qian-Yun Sun ,  Fu-Mei Yang ,  Xin Fang ,  Shun-Lin Li ,  Hua-Jie Zhu ,  Xiao-Jiang Hao
Affiliations
  • 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
PMID: 17655260 DOI: 10.1021/np0700624
Abstract

Four new trijugin-type limonoids, cipatrijugins A-D (1-4), together with the known cipadesin A (5), were isolated from the leaves of Cipadessa cinerascens, and their structures were elucidated on the basis of spectroscopic and computational methods. The ability of compounds 1-5 to inhibit the growth of the A549 and K562 tumor cell lines was evaluated.