Fujenal, a diterpenoid saga of neighbouring group participation

  • Phytochemistry. 2008 Aug;69(11):2104-9. doi: 10.1016/j.phytochem.2008.05.009.
James R Hanson  1 ,  Braulio M Fraga
Affiliations
  • 1. Department of Chemistry, University of Sussex, Brighton, Sussex, BN1 9QJ, UK.
PMID: 18589462 DOI: 10.1016/j.phytochem.2008.05.009
Abstract

The chemistry, the biosynthesis and the biotransformations related to fujenal and its analogues are reviewed. Despite the opportunity for free rotation about the C-9:C-10 bond, the chemistry of the ring B of this diterpenoid is dominated by neighbouring group participation between C-6, C-7 and C-19.

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