Greener biocatalytic approach to the synthesis of nucleosides and their precursors

  • Nucleic Acids Symp Ser (Oxf). 2008;(52):273-4. doi: 10.1093/nass/nrn138.
Sunil K Singh  1 Raman K Sharma Jyotirmoy Maity Jesper Wengel Virinder S Parmar Ashok K Prasad
Affiliations
  • 1. Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi-110 007, India.
Abstract

Novel, efficient and selective biocatalytic acylation / deacylation strategies have been used for the greener synthesis of precursors of different bicyclonucleosides. Biocatalytic methodology has also been developed for the separation of pyrano- and furanonucleosides, which is otherwise almost impossible to achieve by usual chemical approach.

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