Inactivation of T5 phage by cis-vaccenic acid, an antivirus substance from Rhodopseudomonas capsulata, and by unsaturated fatty acids and related alcohols

  • FEMS Microbiol Lett. 1991 Jan 1;61(1):13-7. doi: 10.1016/0378-1097(91)90006-v.
H Hirotani  1 ,  H Ohigashi ,  M Kobayashi ,  K Koshimizu ,  E Takahashi
Affiliations
  • 1. Department of Agricultural Chemistry, Faculty of Agriculture, Kyoto University, Japan.
PMID: 2004693 DOI: 10.1016/0378-1097(91)90006-v
Abstract

The Antiviral extract from Rhodopseudomonas capsulata was purified and the predominant active component was defined as cis-vaccenic acid (Cl-8:1 delta 11) by gas-liquid chromatography and gas chromatography-mass spectrometry analyses. Antiviral activities of unsaturated fatty acids and related alcohols against T5 phage were also tested. Among them, linoelaidic acid, oleic acid, and petroselenyl alcohol inactivated 98%, 53%, 67% of T5 phage at the concentration of 50 micrograms/ml, respectively.

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