Limonoids from the fruits of Melia toosendan

  • Phytochemistry. 2012 Jan;73(1):106-13. doi: 10.1016/j.phytochem.2011.10.001.
Yi Zhang  1 ,  Chun-Ping Tang ,  Chang-Qiang Ke ,  Xi-Qiang Li ,  Hua Xie ,  Yang Ye
Affiliations
  • 1. Department of Natural Products Chemistry and Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.
PMID: 22041666 DOI: 10.1016/j.phytochem.2011.10.001
Abstract

Fifteen limonoids, meliatoosenins E-S (1-15), and 10 known compounds were isolated from the fruits of Melia toosendan. Their structures were elucidated on the basis of extensive spectroscopic methods including DEPT, HSQC, HMBC, (1)H-(1)H COSY, and ROESY experiments. All the compounds were evaluated for antiproliferative activity using A-549 and HL-60 cell lines.

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