A new hydroxychavicol dimer from the roots of Piper betle

  • Molecules. 2013 Feb 26;18(3):2563-70. doi: 10.3390/molecules18032563.
Chwan-Fwu Lin  1 ,  Tsong-Long Hwang ,  Chun-Chien Chien ,  Huei-Yu Tu ,  Horng-Liang Lay
Affiliations
  • 1. Department of Cosmetic Science, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan. [email protected]
PMID: 23442932 DOI: 10.3390/molecules18032563
Abstract

A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of Elastase by human neutrophils.

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