Safety assessment of 6-hydroxyindole as used in cosmetics

  • Int J Toxicol. 2014 Sep-Oct;33(3 Suppl):24S-35S. doi: 10.1177/1091581814533972.
Christina L Burnett  1 ,  Bart Heldreth  2 ,  Wilma F Bergfeld  3 ,  Donald V Belsito  3 ,  Ronald A Hill  3 ,  Curtis D Klaassen  3 ,  Daniel C Liebler  3 ,  James G Marks Jr  3 ,  Ronald C Shank  3 ,  Thomas J Slaga  3 ,  Paul W Snyder  3 ,  F Alan Andersen  4
Affiliations
  • 1. Cosmetic Ingredient Review Scientific Analyst/Writer, Washington, DC, USA.
  • 2. Cosmetic Ingredient Review Chemist, Washington, DC, USA.
  • 3. Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
  • 4. Former Director, Cosmetic Ingredient Review, Washington, DC, USA.
PMID: 25297906 DOI: 10.1177/1091581814533972
Abstract

The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of 6-hydroxyindole, which functions as an oxidative hair dye ingredient. The Panel considered relevant animal and human data provided in this safety assessment and concluded that 6-hydroxyindole is safe for use in oxidative hair dye formulations.

Keywords
6-Hydroxyindole; cosmetics; safety.
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