The selectivity of Marinopyrrole A to induce apoptosis in MCL1high BCL2low expressing myeloma cells is related to its ability to impair protein translation

  • Br J Haematol. 2018 Jan;180(1):157-159. doi: 10.1111/bjh.14293.
Patricia Gomez-Bougie  1 ,  Christelle Dousset  1 ,  Geraldine Descamps  1 ,  Anne Schnitzler  1 ,  Logan Audiger  2 ,  Arnaud Tessier  2 ,  Didier Dubreuil  2 ,  Jacques Lebreton  2 ,  Catherine Pellat-Deceunynck  1 ,  Martine Amiot  1
Affiliations
  • 1. CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
  • 2. UMR_6230, CHEM-Symbiose, Nantes, France.
PMID: 27523575 DOI: 10.1111/bjh.14293
Keywords
BCL2 family members; MCL1; apoptosis; myeloma; translation.
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