Two new alkaloids from the sepals of Solanum melongena L

  • Nat Prod Res. 2021 Nov;35(21):3569-3577. doi: 10.1080/14786419.2020.1713126.
Dong-Ying Zhao  1 ,  Yan Liu  1 ,  Xin Yin  2 ,  Xiao-Mao Li  1 ,  Juan Pan  1 ,  Wei Guan  1 ,  Bing-You Yang  1 ,  Hai-Xue Kuang  1
Affiliations
  • 1. Key Laboratory of Chinese Materia Medica, Ministry of Education of Heilongjiang University of Chinese Medicine, Harbin, P.R. China.
  • 2. College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, P.R. China.
PMID: 31951465 DOI: 10.1080/14786419.2020.1713126
Abstract

Two new Alkaloids named Melongenamides H-I (1-2), together with twenty-one known compounds (3-23), were isolated from the 70% ethanol extract of the sepals of Solanum melongena L. The structures of all isolated compounds were determined by 1D and 2D NMR spectra and by comparing their spectroscopic and physical data with values from the published literatures. All the isolated compounds were evaluated the cytotoxicity against three human canner lines (Hela, Ishikawa and MGC-803) by CCK8 assay.

Keywords
Solanaceae; Solanum melongena L; alkaloid; cytotoxicity; natural product.
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