Structural studies on minor components of saframycin group antibiotics saframycins F, G and H

  • J Antibiot (Tokyo). 1988 Jun;41(6):734-40. doi: 10.7164/antibiotics.41.734.
Y Mikami  1 ,  K Takahashi ,  K Yazawa ,  C Hour-Young ,  T Arai ,  N Saito ,  A Kubo
Affiliations
  • 1. Department of Experimental Chemotherapy, Chiba University, Japan.
PMID: 3403367 DOI: 10.7164/antibiotics.41.734
Abstract

Three minor components of saframycin group Antibiotics, saframycins F, G and H were isolated and their structures were determined by comparison with the spectral data of UV, IR, and 1H and 13C NMR of already reported saframycins A and D. Saframycins F, G and H were 21-cyanosaframycin D, 14-hydroxysaframycin A and 25-dihydro-25-beta-ketopropyl-saframycin A, respectively.

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