Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics

  • Int J Toxicol. 2022 Dec;41(3_suppl):77-128. doi: 10.1177/10915818221124809.
Laura N Scott  1 ,  Monice Fiume  2 ,  Wilma F Bergfeld  3 ,  Donald V Belsito  3 ,  Ronald A Hill  4 ,  Curtis D Klaassen  3 ,  Daniel C Liebler  4 ,  James G Marks Jr  4 ,  Ronald C Shank  4 ,  Thomas J Slaga  3 ,  Paul W Snyder  3 ,  Bart Heldreth  5
Affiliations
  • 1. 44002Former Cosmetic Ingredient Review Scientific Analyst/Writer.
  • 2. 44002Cosmetic Ingredient Review Senior Director.
  • 3. 44002Expert Panel for Cosmetic Ingredient Safety Member.
  • 4. 44002Former Expert Panel for Cosmetic Ingredient Safety Member.
  • 5. 44002Cosmetic Ingredient Review Executive Director.
PMID: 36177798 DOI: 10.1177/10915818221124809
Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Panthenol, Pantothenic Acid, and 5 derivatives as used in cosmetics. These ingredients named in this report are reported to function in cosmetics as hair conditioning agents, and Panthenol also is reported to function as a skin-conditioning agent-humectant and a solvent. The Panel reviewed relevant data for these ingredients, and concluded that these 7 ingredients are safe in cosmetics in the present practices of use concentration described in this safety assessment.

Keywords
cosmetics; panthenol; pantothenic acid; safety.
Products