Constituents of Tritonia crocosmaeflora, I. Tricrozarin A, a novel antimicrobial naphthazarin derivative

  • J Nat Prod. 1987 May-Jun;50(3):418-21. doi: 10.1021/np50051a012.
K Masuda  1 ,  S Funayama ,  K Komiyama ,  I Umezawa ,  K Ito
Affiliations
  • 1. Kitasato Institute, Tokyo, Japan.
PMID: 3668558 DOI: 10.1021/np50051a012
Abstract

A novel naphthazarin derivative, tricrozarin A, has been isolated from the fresh bulbs of Tritonia crocosmaeflora and was characterized as 5,8-dihydroxy-2,3-dimethoxy-6,7-methylenedioxy-1,4-naphthoquinone (2,3-dimethoxy-6,7-methylenedioxynaphthazarin). Tricrozarin A exhibits antimicrobial activity against gram-positive bacteria, fungi, and yeast in vitro and is the first tetra-oxygenated naphthazarin derivative isolated from higher Plants.

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