New antitumor antibiotic, LL-C10037 alpha. Fermentation, isolation and structure determination

  • J Antibiot (Tokyo). 1984 Oct;37(10):1149-52. doi: 10.7164/antibiotics.37.1149.
M D Lee ,  A A Fantini ,  G O Morton ,  J C James ,  D B Borders ,  R T Testa
PMID: 6548735 DOI: 10.7164/antibiotics.37.1149
Abstract

A new antitumor Antibiotic, LL-C10037 alpha was isolated from the fermentation filtrate of a Streptomyces by adsorption, partition and reverse phase column chromatography. Its chemical structure was determined by 1H NMR, 13C NMR, UV, IR and mass spectral data. LL-C10037 alpha is a gamma-aminoepoxysemiquinone and is related to the epoxyguinone class of Antibiotics.

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