(R)-Indeloxazine benzenesulfonate
(R)-Indeloxazine benzenesulfonate (AS1069562) is an orally active 5-HT and NE reuptake inhibitor, with IC50 values of 0.35 μM and 3.3 μM, respectively. (R)-Indeloxazine benzenesulfonate (AS1069562) possesses curative-like analgesic effect. (R)-Indeloxazine benzenesulfonate (AS1069562) might improve nerve function impairment via the amelioration of neurotrophic support.
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- CAS No.: 1623762-83-3
- Formula: C20H23NO5S
- Molecular Weight:389.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
(R)-Indeloxazine benzenesulfonate (AS1069562, STZ-induced diabetic rats, orally, 3, 10, and 30 mg/kg) significantly restores decreased insulin-like growth factor 1 and fibroblast growth factor 2 mRNA levels in dorsal root ganglion and spinal cord, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1623762-83-3
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Molecular Weight 389.47
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Formula C20H23NO5S
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SMILES
O=S(O)(C1=CC=CC=C1)=O.[C@@H]2(CNCCO2)COC3=C4C(C=CC4)=CC=C3
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Synonyms
AS1069562; (R)-YM-08054 benzenesulfonate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)