Rapavir
Rapavir (JH-B10) is a selective and potent sodium taurocholate cotransporting polypeptide (NTCP) inhibitor with an IC50 value of 1.8 nM for the uptake of taurocholic acid-d4 (TCA-d4). Rapavir exerts antiviral activity by directly binding to NTCP and blocking the entry of the virus into cells during the HBV infection phase. Rapavir is promising for research of HBV infections.
For research use only. We do not sell to patients.
- Formula: C68H79FN6O15
- Molecular Weight:1239.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 1239.38
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Formula C68H79FN6O15
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SMILES
O=C(COC1=CC([C@@H](CCC2=CC=C(C(OC)=C2)OC)OC([C@@H]3CCCCN3C4=O)=O)=CC=C1)N(C)CC(N[C@H](C(N([C@H](C(N[C@H](C(N(C)CC/C=C/C(OCC(C)(C4=O)C)=O)=O)CC5=CC=C(C=C5)F)=O)CC6=CC=CC=C6)C)=O)CC7=CC=C(C=C7)O)=O
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Synonyms
JH-B10
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)