ABCB10 Protein, Human (HEK293, Flag, His, E659Q)
ABCB10 Protein, Human (HEK293, Flag, His, E659Q) is the recombinant human-derived ABCB10, expressed by HEK293, with His, Flag labeled tag.
- Species: Human
- Source: HEK293
-
Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
ABCB10 Protein, Human (HEK293, Flag, His, E659Q) is the recombinant human-derived ABCB10, expressed by HEK293, with His, Flag labeled tag.
Background
ABCB10 is an ATP-dependent transporter located in the mitochondrial inner membrane that catalyzes the export of biliverdin from the mitochondrial matrix and plays a crucial role in hemoglobin synthesis and antioxidative stress. It participates in the early step of the heme biosynthetic process during the insertion of iron into protoporphyrin IX (PPIX). Additionally, ABCB10 is involved in the stabilization of the iron transporter mitoferrin-1/SLC25A37 (by similar). While ABCB10 likely does not participate in peptide export from mitochondria, it may be involved in the mitochondrial unfolded protein response (UPRmt) signaling pathway.
Technical Parameters
-
Species Human
-
Source HEK293
-
Tag His;Flag
-
Accession
Q9NRK6 (A152-A738, E659Q)
-
Gene ID23456
-
Protein Length
Partial
-
Synonyms
ABCB10; ABC Transporter 10 Protein; ATP Binding Cassette Subfamily B Member 10; EST20237; M-ABC2; MTABC2; ATP-Binding Cassette Sub-Family B Member 10, Mitochondrial; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 10; Mitochondrial ATP-Binding Casset
-
AA Sequence
AGLPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDQATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAVLDQGKITEYGKHEELLSKPNGIYRKLMNKQSFISA
-
Predicted Molecular Mass
67.1 kDa
-
Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
