Aconitase 2/ACO2 Protein, Human (sf9, His-GST)

Aconitase 2/ACO2 Protein, an enzyme, plays a vital role in the tricarboxylic acid cycle and energy production. Dysregulation of Aconitase 2/ACO2 Protein has been associated with mitochondrial dysfunction and oxidative stress. Targeting Aconitase 2/ACO2 Protein may provide potential therapeutic strategies by regulating energy metabolism, reducing oxidative damage, and improving mitochondrial function. Aconitase 2/ACO2 Protein, Human (sf9, His-GST) is the recombinant human-derived Aconitase 2/ACO2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Aconitase 2/ACO2 Protein, Human (sf9, His-GST) is 753 a.a., with molecular weight of ~110 kDa.

The Aconitase 2/ACO2 protein emerges as a pivotal catalyst in cellular processes, facilitating the isomerization of citrate to isocitrate through the intermediate cis-aconitate. This enzymatic activity is instrumental in key metabolic pathways, contributing to the dynamic regulation of citric acid cycle intermediates. The ACO2 protein's role in orchestrating the conversion of citrate to isocitrate underscores its significance in maintaining cellular energy balance and metabolic homeostasis.

Human

Sf9 insect cells

N-His;N-GST

Q99798 (Q28-Q780)

50  [NCBI]

Approximately 110 kDa

Greater than 85% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.