Animal-Free IL-31 Protein, Mouse (His)
Based on 1 Customer Validation
IL-31 Protein activates STAT3, potentially STAT1 and STAT5, through the IL31 receptor. It enhances myeloid progenitor cell survival and induces RETNLA and serum amyloid A protein expression in macrophages. IL-31 Protein's diverse functions suggest its importance in biological processes and potential implications in immune regulation and cell survival. Animal-Free IL-31 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-31 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.
- Species: Mouse
- Source: E. coli
-
Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
IL-31 Protein activates STAT3, potentially STAT1 and STAT5, through the IL31 receptor. It enhances myeloid progenitor cell survival and induces RETNLA and serum amyloid A protein expression in macrophages. IL-31 Protein's diverse functions suggest its importance in biological processes and potential implications in immune regulation and cell survival. Animal-Free IL-31 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-31 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.
Background
IL-31 Protein activates STAT3 and potentially STAT1 and STAT5 through the IL31 heterodimeric receptor, which consists of IL31RA and OSMR. It has been suggested to play a role in skin immunity and enhances the survival of myeloid progenitor cells in vitro. IL-31 Protein also induces the expression of RETNLA and serum amyloid A protein in macrophages. These diverse functions highlight the significance of IL-31 Protein in various biological processes and suggest its potential implications in immune regulation and cell survival.
Technical Parameters
-
Species Mouse
-
Source E. coli
-
Tag C-6*His
-
Accession
Q6EAL8 (T24-C163)
-
Molecular Construction
-
N-term
-
IL-31 (T24-C163)
Accession # Q6EAL8 -
6*His
-
C-term
-
-
Protein Length
Full Length of Mature Protein
-
Synonyms
IL31; IL-31; Interleukin 31; Interleukin-31
-
AA Sequence
TCSLSFGAPISKEDLRTTIDLLKQESQDLYNNYSIKQASGMSADESIQLPCFSLDREALTNISVIIAHLEKVKVLSENTVDTSWVIRWLTNISCFNPLNLNISVPGNTDESYDCKVFVLTVLKQFSNCMAELQAKDNTTC
-
Predicted Molecular Mass
16.6 kDa
-
Molecular Weight
Approximately 17 kDa, based on SDS-PAGE under reducing conditions.
-
Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, trehalose.
<0.1 EU per 1 μg of the protein by the LAL method.
It is recommended to reconstitute to a concentration of 100-200 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
-
Data Sheet (235 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
