Cadherin-3 Protein, Human (547a.a, HEK293, His)

Cadherin-3 protein, a calcium-dependent adhesion molecule, facilitates cell interactions. It prefers homophilic interaction with other cadherin-3 proteins, aiding cell connection. This interaction helps sort and organize cell types. Cadherin-3 also interacts with CDCP1 and CTNNB1, impacting cellular processes. Cadherin-3 Protein, Human (547a.a, HEK293, His) is the recombinant human-derived Cadherin-3 protein, expressed by HEK293 , with C-His labeled tag.

Cadherin-3 is a calcium-dependent cell adhesion protein that plays a vital role in cell-to-cell interactions. It exhibits a strong preference for interacting with other cadherin-3 proteins in a homophilic manner, facilitating the connection between adjacent cells. This specific interaction enables cadherin-3 to contribute to the sorting and organization of diverse cell types within tissues. Additionally, cadherin-3 is known to interact with CDCP1 and CTNNB1, further influencing cellular processes.

Immobilized Anti-CDH3 Antibody, hFc Tag at 2 μg/mL (100 μl/Well) on the plate. Dose response curve for Human CDH3, His Tag with the EC₅₀ of ≤3 μg/mL determined by ELISA.

Human

HEK293

C-8*His

P22223 (D108-G654)

1001  [NCBI]

Extracellular Domain

DWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETCPGPWKGG

70-80 kDa

≥ 95%, as determined by Bis-Tris PAGE.

Lyophilized powder

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.