CAMK1 delta Protein, Human (Active, sf9, GST)
CAMK1 delta Protein, Human (sf9, GST) is the recombinant human-derived CAMK1 delta, expressed by Sf9 insect cells , with GST labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Biological Activity
Description
CAMK1 delta Protein, Human (sf9, GST) is the recombinant human-derived CAMK1 delta, expressed by Sf9 insect cells , with GST labeled tag.
Background
CAMK1 delta is a calcium/calmodulin-dependent protein kinase that functions within the calcium-triggered CaMKK-CaMK1 signaling cascade. Upon calcium influx, it activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst, and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, it is required for cytokine-induced proliferative responses and activation of the respiratory burst. CAMK1 delta also activates the transcription factor CREB1 in hippocampal neuron nuclei and may play a role in apoptosis of erythroleukemia cells. In vitro, it phosphorylates the transcription factor CREM isoform Beta.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag GST
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Accession
Q8IU85-1 (A2-K385)
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Gene ID57118
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Protein Length
Full Length of Isoform-1
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Synonyms
CAMK1; CaM Kinase I Alpha; Calcium/Calmodulin Dependent Protein Kinase I; CaM-KI; CaMKI-Alpha; Calcium/Calmodulin-Dependent Protein Kinase; CaMKI; CaM Kinase I; Calcium/Calmodulin-Dependent Protein Kinase Type 1
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AA Sequence
ARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)