Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO)
Cathelicidin-4/CATHL4 protein has potent bactericidal activity and can effectively target Staphylococcus aureus and Escherichia coli. This antibacterial ability makes cathelicidin-4 an important innate immune effector that contributes to host defense against bacterial pathogens. Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO) is the recombinant bovine-derived Cathelicidin-4/CATHL4 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
- Species: Bovine
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Biological Activity
Description
Cathelicidin-4/CATHL4 protein has potent bactericidal activity and can effectively target Staphylococcus aureus and Escherichia coli. This antibacterial ability makes cathelicidin-4 an important innate immune effector that contributes to host defense against bacterial pathogens. Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO) is the recombinant bovine-derived Cathelicidin-4/CATHL4 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
Background
Cathelicidin-4/CATHL4 Protein exhibits potent microbicidal activity, demonstrating effectiveness against both S. aureus and E. coli. This antimicrobial property underscores the significance of Cathelicidin-4 in host defense mechanisms, highlighting its role as an innate immune effector capable of combating bacterial pathogens. The broad-spectrum antimicrobial activity against Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria emphasizes the versatility of Cathelicidin-4, making it a valuable component of the host's arsenal in the ongoing battle against microbial invaders.
Technical Parameters
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Species Bovine
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Source E. coli
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Tag N-His;N-SUMO
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Accession
P33046 (I131-R143)
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Gene ID282166 [NCBI]
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Molecular Construction
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N-term
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6*His-SUMO
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CATHL4 (I131-R143)
Accession # P33046 -
C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
CATHL4; Indolicidin; Cathelicidin-4
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AA Sequence
ILPWKWPWWPWRR
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Predicted Molecular Mass
17.9 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)