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  6. CD64 Protein, Canine (HEK293, His)

CD64 Protein, Canine (HEK293, His) is the recombinant canine-derived CD64 protein, expressed by HEK293, with C-His tag.

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CD64 Protein, Canine (HEK293, His) is the recombinant canine-derived CD64 protein, expressed by HEK293, with C-His tag.
Background

CD64 Protein, characterized by its leukotriene receptor binding activity, plays a crucial role in various biological processes, including the positive regulation of phagocytosis and the sensory perception of pain, as well as the response to epinephrine. Situated in membrane rafts, CD64, encoded by the FCGR1A gene, exhibits a biased expression pattern with notable levels in the Spleen (RPKM 177.3), Lung (RPKM 93.7), and nine other tissues. This underlines its significance in immune responses and sensory functions across diverse physiological contexts.
Species

Canine
Source

HEK293
Tag

C-His
Accession

NP_001002976.1 (V11-P288)
Gene ID

403462
Protein Length

Partial
Synonyms
High affinity immunoglobulin gamma Fc receptor I; Fcgr1; FcRI; CD64; Fc receptor; IgG; high affinity I
AA Sequence

VPAGAQTDPVKAVITLQPPWVSVFQEESVTLWCEGPHLPGDSSTQWFLNGTATQTLTPRYRIAAASVNDNGEYRCQTGLSVLSDPIQLGIHRDWLILQVSGRVFTEGEPLTLRCHGWNNKLVYNVLFYQNGTVLKFSPQNSEFTILKTTLHHNGIYHCSAMGKHRYESAGVSITIKELFPAPVLKASLSSPILEGHVVNLSCETKLLLQRPGLQLYFSFYMGSKTLLSRNTSSEYQILTAKKEDSGLYWCEATTEDGNVVKRSPELELQVVGPQTLTP

Predicted Molecular Mass
31.9 kDa
분자량

Approximately 43.6 kDa & 40.2 kDa,based on SDS-PAGE under reducing conditions.
Purity

≥ 95%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
각종 서류
Handling Instructions (2659 KB)

CD64 Protein, Canine (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CD64 Protein, Canine (HEK293, His)
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HY-P703825
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