Claudin-6/CLDN6 Protein-VLP, Human (HEK293)
Claudin-6/CLDN6 Protein-VLP, Human (HEK293) is recommended for SPR analysis, animal immunization, ELISA, PK assay. May have binding signals with Anti-His antibodies.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Biological Activity
Description
Claudin-6/CLDN6 Protein-VLP, Human (HEK293) is recommended for SPR analysis, animal immunization, ELISA, PK assay. May have binding signals with Anti-His antibodies.
Background
The Claudin-6/CLDN6 protein-VLP plays a crucial role in the specific obliteration of the intercellular space in tight junctions. It is involved in maintaining the integrity of the cell barrier, preventing leakage and maintaining cell polarity. Additionally, the protein acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells, facilitating viral infection.
Technical Parameters
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Species Human
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Source HEK293
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Tag Tag Free
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Accession
P56747 (M1-V220)
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Gene ID9074
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Molecular Construction
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N-term
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CLDN6 (M1-V220)
Accession # P56747 -
C-term
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Protein Length
Full Length
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Synonyms
CLDN6; Claudin-6; Claudin 6; Skullin
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AA Sequence
MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV
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Predicted Molecular Mass
24.5 kDa
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Purity
≥ 95%, as determined by HPLC.
Product Properties
Lyophilized powder
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (236 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)