CNDP2 Protein, Mouse (sf9, His)
CNDP2 Protein, Mouse (sf9, His) is the recombinant mouse-derived CNDP2 protein, expressed by Sf9 insect cells, with C-His tag.
- Species: Mouse
- Source: Sf9 insect cells
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Biological Activity
CNDP2 Protein, Mouse (sf9, His) is the recombinant mouse-derived CNDP2 protein, expressed by Sf9 insect cells, with C-His tag.
HO-2/HMOX2 protein serves as a catalyst in the oxidative cleavage of heme at the alpha-methene bridge carbon, liberating carbon monoxide (CO) and producing biliverdin IXalpha. This enzymatic process results in the release of the central heme iron chelate as ferrous iron. HO-2/HMOX2 plays a crucial role in the breakdown of heme, facilitating the controlled generation of signaling molecules such as CO and biliverdin. The release of CO, in particular, has various physiological implications, contributing to vascular homeostasis, anti-inflammatory responses, and cellular protection. This enzyme's activity is integral to the regulation of heme metabolism and the maintenance of cellular redox balance.
Technical Parameters
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Species Mouse
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Source Sf9 insect cells
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Tag C-His
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Accession
NP_075638.2 (M1-N475)
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Gene ID66054
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Protein Length
Full Length
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Synonyms
CNDP2; Glutamate Carboxypeptidase-Like Protein 1; Prev. PEPA; Carnosine Dipeptidase II; CPGL; CNDP Dipeptidase 2; CN2; Carnosinase-2; Cytosolic Non-Specific Dipeptidase; FLJ10830; Threonyl Dipeptidase; HEL-S-13; Peptidase A; Epididymis Secretory Protein L
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AA Sequence
MSALKAVFQYIDENQDRYVKKLAEWVAIQSVSAWPEKRGEIRRMMEVAAADVQRLGGSVELVDIGKQKLPDGSEIPLPPILLGKLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLVEREGKLYGRGSTDDKGPVAGWMNALEAYQKTGQEIPVNLRFCLEGMEESGSEGLDELIFAQKDKFFKDVDYVCISDNYWLGKNKPCITYGLRGICYFFIEVECSDKDLHSGVYGGSVHEAMTDLISLMGCLVDKKGKILIPGINDAVAPVTDEEHALYDHIDFDMEEFAKDVGAETLLHSCKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPDMIPEVVSEQVSSYLSKKFAELQSPNKFKVYMGHGGKPWVSDFNHPHYQAGRRALKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRLNYIEGTKMLAAYLYEVSQLKN
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Predicted Molecular Mass
54.2 kDa
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Molecular Weight
Approximately 50 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)