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  3. Isomerases (EC 5)
  4. CRELD1 Protein, Mouse (HEK293, Fc)

CRELD1 Protein, Mouse (HEK293, Fc)

Cat. No.: HY-P76286
Handling Instructions

The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CRELD1 Protein, Mouse (HEK293, Fc) is 362 a.a., with molecular weight of ~63 KDa.

For research use only. We do not sell to patients.

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Description

The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CRELD1 Protein, Mouse (HEK293, Fc) is 362 a.a., with molecular weight of ~63 KDa.

Background

CRELD1 Protein, identified as a member of the protein disulfide isomerase family, plays a significant role in cellular processes. This protein, akin to other members of the family, is involved in disulfide bond rearrangement. Notably, CRELD1 has been found to facilitate the localization of acetylcholine receptors (AChRs) to the plasma membrane. This function underscores the importance of CRELD1 in the organization and positioning of key cellular components, particularly the acetylcholine receptors, highlighting its potential impact on cellular communication and signaling processes.

Species

Mouse

Source

HEK293

Tag

C-hFc

Accession

Q91XD7 (M1-E362)

Gene ID

171508  [NCBI]

Molecular Construction
N-term
CRELD1 (M1-E362)
Accession # Q91XD7
hFc
C-term
Synonyms
Protein disulfide isomerase CRELD1; Cysteine-rich with EGF-like domain protein 1; CIRRIN
Molecular Weight

Approximately 63 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

CRELD1 Protein, Mouse (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CRELD1 Protein, Mouse (HEK293, Fc)
Cat. No.:
HY-P76286
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