CRELD1 Protein, Mouse (HEK293, Fc)
The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-hFc labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-hFc labeled tag.
Background
CRELD1 Protein, identified as a member of the protein disulfide isomerase family, plays a significant role in cellular processes. This protein, akin to other members of the family, is involved in disulfide bond rearrangement. Notably, CRELD1 has been found to facilitate the localization of acetylcholine receptors (AChRs) to the plasma membrane. This function underscores the importance of CRELD1 in the organization and positioning of key cellular components, particularly the acetylcholine receptors, highlighting its potential impact on cellular communication and signaling processes.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-hFc
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Accession
Q91XD7 (Q30-E362)
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Molecular Construction
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N-term
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CRELD1 (Q30-E362)
Accession # Q91XD7 -
hFc
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C-term
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Protein Length
Extracellular Domain
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Synonyms
CRELD1; Cysteine-Rich With EGF-Like Domain Protein 1; Prev. AVSD2; Atrioventricular Septal Defect 2; Cysteine Rich With EGF Like Domains 1; Protein Disulfide-Isomerase; CIRRIN; JELANS; CRELD Disulfide Isomerase 1; Protein Disulfide Isomerase CRELD1
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AA Sequence
QPSPPPHPSPRAEPHPCHTCRALVDNFNKGLERTIRDNFGGGNTAWEEEKLSKYKDSETRLVEVLEGVCSRSDFECHRLLELSEELVENWWFHRQQEAPDLFQWLCSDSLKLCCPSGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNSSHLVCSACFGPCARCTGPEESHCLQCKKGWALHHLKCVDIDECGTEQATCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSRGYQQVGSKCLDVDECETVVCPGENEKCENTEGGYRCVCAEGYRQEDGICVKEQVPESAGFFAEMTEDE
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Predicted Molecular Mass
63 kDa
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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