GM-CSF Protein, Human (P.pastoris, N-His)

The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GM-CSF Protein, Human (P.pastoris, N-His) is the recombinant human-derived GM-CSF protein, expressed by P. pastoris , with N-6*His labeled tag.

GMP GM-CSF Protein functions as a pivotal cytokine, fostering the growth and differentiation of hematopoietic precursor cells spanning diverse lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GMP GM-CSF serves as a signaling molecule, orchestrating a complex receptor assembly. This receptor complex takes the shape of a dodecamer, consisting of two head-to-head hexamers, each composed of two alpha, two beta, and two ligand subunits. This structural intricacy underscores the specificity and regulatory role of GMP GM-CSF in directing cellular responses within the hematopoietic system.

Human

P. pastoris

N-6*His

P04141 (A18-E144)

1437  [NCBI]

Full Length of Mature Protein

APARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE

≥ 90%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.