1. Recombinant Proteins
  2. CD Antigens
  3. Dendritic Cell CD Proteins
  4. DEC-205/CD205
  5. DEC-205/CD205 Protein, Mouse (HEK293, His)

DEC-205/CD205 Protein, Mouse (HEK293, His)

Cat. No.: HY-P77992
COA Handling Instructions

DEC-205/CD205 protein acts as an endocytic receptor, directing antigens to an antigen-processing compartment. It also reduces B lymphocyte proliferation. DEC-205/CD205 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DEC-205/CD205 protein, expressed by HEK293, with C-His labeled tag. The total length of DEC-205/CD205 Protein, Mouse (HEK293, His) is 1640 a.a., with molecular weight of 235-250 kDa.

For research use only. We do not sell to patients.

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Description

DEC-205/CD205 protein acts as an endocytic receptor, directing antigens to an antigen-processing compartment. It also reduces B lymphocyte proliferation. DEC-205/CD205 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DEC-205/CD205 protein, expressed by HEK293, with C-His labeled tag. The total length of DEC-205/CD205 Protein, Mouse (HEK293, His) is 1640 a.a., with molecular weight of 235-250 kDa.

Background

The DEC-205/CD205 protein functions as an endocytic receptor, responsible for directing captured antigens from the extracellular space to a specialized antigen-processing compartment. Additionally, it has been observed to cause reduced proliferation of B lymphocytes (By similarity).

Species

Mouse

Source

HEK293

Tag

C-His

Accession

Q60767 (S28-D1667)

Gene ID

17076  [NCBI]

Molecular Construction
N-term
CD205 (S28-D1667)
Accession # Q60767
His
C-term
Synonyms
Ly-75; DEC-205; CD205; CLEC13B; GP200-MR6
Molecular Weight

235-250 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

DEC-205/CD205 Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
DEC-205/CD205 Protein, Mouse (HEK293, His)
Cat. No.:
HY-P77992
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