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  3. DRD2 Protein, Human (sf9, Flag, His)

DRD2 Protein, Human (sf9, Flag, His) is the recombinant human-derived DRD2, expressed by sf9 insect cells , with His, Flag labeled tag. ,

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  • Actividad biológica

  • Technical Parameters

  • Properties

  • Descripciòn

Descripciòn

DRD2 Protein, Human (sf9, Flag, His) is the recombinant human-derived DRD2, expressed by sf9 insect cells , with His, Flag labeled tag. ,

Background

DRD2 is a dopamine receptor whose activity is mediated by G proteins that inhibit adenylyl cyclase. Additionally, downstream of OPN5, DRD2 positively regulates postnatal regression of retinal hyaloid vessels by suppressing VEGFR2/KDR activity.

Species

Human

Source

Sf9 insect cells

Tag

His;Flag

Accession

P14416-1 (N35-V223, R361-C443, I122A, L375A, L379A)

Gene ID

1813

Protein Length

Partial

Synonyms
D(2) dopamine receptor; Dopamine D2 receptor; DRD2; Homo sapiens; Human; G-protein coupled receptor; Receptor; Transducer
AA Sequence

RKLSQQKEKKATQMAAIVAGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC

Peso molecular

Approximately 52 kDa, based on SDS-PAGE under reducing conditions.

Pureza

≥ 80%, as determined by reducing SDS-PAGE.

Appearance

Solution.

Formulation

Supplied as a 0.22 μm filtered solution of 20 mM HEPES, pH 7.5, 150 mM NaCl, 0.01% , w/v LMNG, 0.001% , w/v CHS, 1 μM risperidone.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

Please use rapid thawing with running water to thaw the protein.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Envío

Shipping with dry ice.

Documentación

DRD2 Protein, Human (sf9, Flag, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Inquiry Information

Nombre del producto:
DRD2 Protein, Human (sf9, Flag, His)
Cat. No.:
HY-P703116
Cantidad:
MCE Japan Authorized Agent: