1. Recombinant Proteins
  2. CD Antigens Receptor Proteins
  3. Endothelial cell CD Proteins Cell Adhesion Molecules (CAMs)
  4. E-Selectin/CD62E Selectin
  5. E-Selectin
  6. E-selectin/CD62E Protein, Cynomolgus (HEK293, hFc)

E-selectin/CD62E Protein, Cynomolgus (HEK293, hFc)

Cat. No.: HY-P75221
Handling Instructions

The E-selectin/CD62E Protein, belonging to the selectin/LECAM family, plays a crucial role in mediating cell adhesion processes, particularly interactions between leukocytes and endothelial cells. As a member of this family, E-selectin likely shares conserved features, emphasizing its significance in cellular adhesion. Its study contributes to understanding inflammatory responses, immune cell trafficking, and potential therapeutic interventions. Further exploration of E-selectin/CD62E's role promises insights into its contributions to immune surveillance, inflammation, and broader cellular processes in both normal physiology and pathology. E-selectin/CD62E Protein, Cynomolgus (HEK293, hFc) is the recombinant cynomolgus-derived E-selectin/CD62E protein, expressed by HEK293, with C-hFc labeled tag. The total length of E-selectin/CD62E Protein, Cynomolgus (HEK293, hFc) is 535 a.a., with molecular weight of ~85.7 kDa.

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Description

The E-selectin/CD62E Protein, belonging to the selectin/LECAM family, plays a crucial role in mediating cell adhesion processes, particularly interactions between leukocytes and endothelial cells. As a member of this family, E-selectin likely shares conserved features, emphasizing its significance in cellular adhesion. Its study contributes to understanding inflammatory responses, immune cell trafficking, and potential therapeutic interventions. Further exploration of E-selectin/CD62E's role promises insights into its contributions to immune surveillance, inflammation, and broader cellular processes in both normal physiology and pathology. E-selectin/CD62E Protein, Cynomolgus (HEK293, hFc) is the recombinant cynomolgus-derived E-selectin/CD62E protein, expressed by HEK293, with C-hFc labeled tag. The total length of E-selectin/CD62E Protein, Cynomolgus (HEK293, hFc) is 535 a.a., with molecular weight of ~85.7 kDa.

Background

The E-selectin/CD62E Protein is a vital member of the selectin/LECAM family, signifying its significant role in cell adhesion processes. As part of this family, E-selectin likely shares conserved structural and functional features with related proteins, indicating its involvement in mediating interactions between leukocytes and endothelial cells. The classification within the selectin/LECAM family underscores its specific designation within the broader context of cell adhesion molecules, providing insights into its unique contributions to cellular adhesion. The study of E-selectin/CD62E contributes to our understanding of its role in inflammatory responses and immune cell trafficking, offering potential applications in therapeutic interventions and a deeper comprehension of its broader impact on cellular processes involved in immune surveillance and inflammation. Further exploration of E-selectin/CD62E's role holds promise for enhancing our knowledge of its contributions to normal physiology and pathological conditions.

Species

Cynomolgus

Source

HEK293

Tag

C-hFc

Accession

G8F370 (W22-P556)

Gene ID

/

Molecular Construction
N-term
CD62E (W22-P556)
Accession # G8F370
hFc
C-term
Synonyms
E-selectin; ELAM-1; LECAM2; CD62E; SELE
Molecular Weight

Approximately 85.7 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

E-selectin/CD62E Protein, Cynomolgus (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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E-selectin/CD62E Protein, Cynomolgus (HEK293, hFc)
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HY-P75221
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