1. Recombinant Proteins
  2. CD Antigens Receptor Proteins
  3. Endothelial cell CD Proteins
  4. CD201/Activated Protein C Receptor
  5. EPCR Protein, Mouse (HEK293, hFc)

EPCR Protein, Mouse (HEK293, hFc)

Cat. No.: HY-P75246
Handling Instructions

EPCR Protein, crucial in the protein C pathway, regulates blood coagulation by binding and enhancing the activation of activated protein C through the thrombin-thrombomodulin complex, ensuring effective control of hemostasis. EPCR Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived EPCR protein, expressed by HEK293, with C-hFc labeled tag. The total length of EPCR Protein, Mouse (HEK293, hFc) is 214 a.a., with molecular weight of 65-75 kDa.

For research use only. We do not sell to patients.

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Description

EPCR Protein, crucial in the protein C pathway, regulates blood coagulation by binding and enhancing the activation of activated protein C through the thrombin-thrombomodulin complex, ensuring effective control of hemostasis. EPCR Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived EPCR protein, expressed by HEK293, with C-hFc labeled tag. The total length of EPCR Protein, Mouse (HEK293, hFc) is 214 a.a., with molecular weight of 65-75 kDa.

Background

The EPCR protein plays a crucial role in the protein C pathway, which regulates blood coagulation. It has the capability to bind activated protein C and acts to enhance its activation by the thrombin-thrombomodulin complex. This interaction is essential for controlling blood coagulation and maintaining proper hemostasis.

Species

Mouse

Source

HEK293

Tag

C-hFc

Accession

Q64695 (M1-S214)

Gene ID

19124  [NCBI]

Molecular Construction
N-term
EPCR (M1-S214)
Accession # Q64695
hFc
C-term
Synonyms
Endothelial Protein C Receptor; CD201; PROCR; EPCR
Molecular Weight

65-75 kDa

Purity

Greater than 85% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

EPCR Protein, Mouse (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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EPCR Protein, Mouse (HEK293, hFc)
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HY-P75246
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