FGA Protein, Human (His)
Based on 1 Customer Validation
FGA Protein, a heterohexamer, features a complex structure with disulfide-linked alpha, beta, and gamma chains forming two distinct sets. The heterotrimeric units adopt a head-to-head conformation, converging at the N-termini in a compact central domain. This unique arrangement highlights the intricate organization of FGA, emphasizing the interplay between its constituent subunits essential for its biological functions. FGA Protein, Human (His) is the recombinant human-derived FGA protein, expressed by E. coli , with N-6*His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
FGA Protein, a heterohexamer, features a complex structure with disulfide-linked alpha, beta, and gamma chains forming two distinct sets. The heterotrimeric units adopt a head-to-head conformation, converging at the N-termini in a compact central domain. This unique arrangement highlights the intricate organization of FGA, emphasizing the interplay between its constituent subunits essential for its biological functions. FGA Protein, Human (His) is the recombinant human-derived FGA protein, expressed by E. coli , with N-6*His labeled tag.
FGA Protein exists as a heterohexamer, intricately structured through disulfide linkages, comprising two distinct sets of three non-identical chains: alpha, beta, and gamma. The heterotrimeric units arrange themselves in a head-to-head conformation, with the N-termini converging in a compact central domain. This unique arrangement underscores the complex organization of FGA, showcasing its structural intricacies and the interplay between its constituent subunits, which are crucial for its functional roles within biological systems.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-6*His
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Accession
Q8WW76 (G36-S218)
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Gene ID/
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Molecular Construction
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N-term
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6*His
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FGA (G36-S218)
Accession # Q8WW76 -
C-term
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Protein Length
Partial
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Synonyms
FGA; Fibrinogen Alpha Chain Isoform 5; Fibrinogen Alpha Chain; FGA Protein; Fibrinogen, A Alpha Polypeptide; AMYLD2; Fibrinogen Alpha Chain Isoform 8; Fib2; Fibrinogen Alpha Chain Isoform 1
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AA Sequence
GPRVVERHQSACKDSDWPFCSGEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVTANNLLVARVTTEETPHLKARAIKWQMRPEVKPIMKEHIAPREAMLNLALSEVSTLLLWGSLPCPPRLS
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Predicted Molecular Mass
25.1 kDa
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Molecular Weight
Approximately 27-30 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
1.Lyophilized from a 0.22 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% trehalose, pH 8.0.
2.Lyophilized from a 0.22 μm filtered solution of PBS, 6% trehalose, pH 7.4.
Please refer to the lot-specific COA for specific buffer information.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (235 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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