FOLR2 Protein, Cynomolgus (HEK293, His)

The FOLR2 protein is a member of the folate receptor family. Folate receptors are cell surface proteins that play a key role in the uptake and transport of folate (vitamin B9) into cells. FOLR2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived FOLR2 protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Cynomolgus
  • Source: HEK293
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

The FOLR2 protein is a member of the folate receptor family. Folate receptors are cell surface proteins that play a key role in the uptake and transport of folate (vitamin B9) into cells. FOLR2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived FOLR2 protein, expressed by HEK293 , with C-His labeled tag.

Background

FOLR2 Protein is a member of the folate receptor family. Folate receptors are cell surface proteins that play a critical role in the uptake and transport of folate (vitamin B9) into cells. FOLR2 is expressed in various tissues, including the placenta, kidney, and lung, although its expression levels are generally lower compared to other folate receptors. Like other members of the folate receptor family, FOLR2 is involved in folate metabolism and may participate in cellular processes such as folate uptake and transport. However, compared to FOLR1, less is known about the specific functions and roles of FOLR2. Further research is needed to fully understand the precise functions and significance of FOLR2 in cellular processes and its potential implications in health and disease.

Technical Parameters

  • Species Cynomolgus
  • Source HEK293
  • Tag C-6*His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • FOLR2 (Q9-H187)
      Accession # A0A2K5U027
    • 6*His
    • C-term
  • Protein Length

    Partial

  • Synonyms

    FOLR2; FOLR2 Protein; Folate Receptor Beta; BETA-HFR; Folate Receptor, Fetal/Placental; FBP/PL-1; Placental Folate-Binding Protein; FR-BETA; Folate Receptor 2 (Fetal); FR-Beta; FBP; FRbeta; Folate-Binding Protein, Fetal/Placental; FR-P3; Folate Receptor A

  • AA Sequence

    QCSPWKKNACCTANTSQELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIRQVNQSWRKERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCLTFESYFPTPVALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFYAAVMH

  • Predicted Molecular Mass

    25.5 kDa

  • Molecular Weight

    Approximately 30-45 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Purity

    ≥ 95%, as determined by Bis-Tris PAGE.

Product Properties

Appearance

Solution

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
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Volume (start) Volume (start)
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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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