Ftl1 Protein, Mouse (His)
Based on 1 Customer Validation
Ferritin light chain 1 (FTL1) is an iron-associated protein that acts as a pro-aging neuronal factor, impairing cognitive function. Ftl1, Mouse (His) is a recombinant mouse Ftl1 protein expressed by E. coli and tagged with C-6*His.
- Species: Mouse
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- References
- Help & FAQs
Biological Activity
Ferritin light chain 1 (FTL1) is an iron-associated protein that acts as a pro-aging neuronal factor, impairing cognitive function. Ftl1, Mouse (His) is a recombinant mouse Ftl1 protein expressed by E. coli and tagged with C-6*His.
FTL1 由铁蛋白的轻链组成，参与铁的长期储存。已知铁代谢紊乱会促进线粒体功能障碍，并导致代谢过程的改变——这是衰老过程的一个关键标志。在海马体中检测到的与年龄相关的神经元 FTL1 水平的增加可能反映了衰老过程中大脑铁代谢的变化[1]。
Technical Parameters
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Species Mouse
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Source E. coli
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Tag C-6*His
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Accession
P29391 (M1-D183)
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Gene ID2512
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Protein Length
Full Length
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Synonyms
FTL; MGC71996; Ferritin Light Chain; Neurodegeneration With Brain Iron Accumulation 3; Ferritin L Subunit; Epididymis Secretory Sperm Binding Protein; NBIA3; Ferritin Light Polypeptide; FTL1; L Apoferritin; Ferritin Light Polypeptide-Like 3; L-Ferritin; F
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AA Sequence
MTSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKREGAERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALAMEKNLNQALLDLHALGSARTDPHLCDFLESHYLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGAPQGSLGEYLFERLTLKHD
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Predicted Molecular Mass
27.7 kDa
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Molecular Weight
Approximately 30 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder
Lyophilized from a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (261 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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